Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 9/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CBR1 | P16152 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537944 | 0.82 | RAB9A (0.56) | SMN1; SMN2L3MBTL1KDRKDM4EMAPT | |
| SCHEMBL6537959 | 0.82 | RAB9A (0.56) | SMN1; SMN2L3MBTL1KDRGAAKDM4E | |
| SCHEMBL6537606 | 0.82 | KDR (0.67) | SMN1; SMN2PTGESL3MBTL1KDRKDM4E | |
| SCHEMBL7522656 | 0.82 | MAPT (0.68) | SMN1; SMN2PTGESL3MBTL1KDRGAA | |
| SCHEMBL30733219 | 0.82 | MAPT (0.68) | SMN1; SMN2PTGESL3MBTL1KDRGAA | |
| SCHEMBL6537986 | 0.81 | KDR (0.50) | SMN1; SMN2RXFP1L3MBTL1KDRGAA | |
| SCHEMBL6537919 | 0.80 | CYP1A2 (0.55) | SMN1; SMN2L3MBTL1LMNAKDM4EMAPT | |
| SCHEMBL6537751 | 0.80 | RAB9A (0.69) | SMN1; SMN2RXFP1GAAKCNK3KCNK9 | |
| SCHEMBL6537757 | 0.78 | KDR (0.58) | SMN1; SMN2RXFP1L3MBTL1KDRGAA | |
| SCHEMBL6537536 | 0.77 | KDR (0.52) | SMN1; SMN2L3MBTL1KDRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |