Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533014 | 1.00 | KDM4E (0.35) | KDM4EKMT2AEPHX1HSD11B1 | |
| SCHEMBL14532886 | 0.94 | KDM4E (0.36) | KDM4EKMT2AEPHX1 | |
| SCHEMBL14533052 | 0.83 | ARG1 (0.32) | HSD11B1 | |
| SCHEMBL14532948 | 0.80 | MAPT (0.41) | KMT2A | |
| SCHEMBL14533054 | 0.77 | CYP1A2 (0.34) | — | |
| SCHEMBL19776560 | 0.76 | — | — | |
| SCHEMBL14533126 | 0.76 | CYP1A2 (0.33) | — | |
| SCHEMBL14532887 | 0.74 | NPSR1 (0.36) | — | |
| SCHEMBL14532952 | 0.73 | — | — | |
| SCHEMBL3347705 | 0.71 | EPHX1 (0.38) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000051973-A1 | CYCLOBUTENE-3,4-DIONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-09-08 | — | — | WO | claimed |