SCHEMBL7523089

SCHEMBL7523089

CCCCCCCCOc1ccc(C(=O)Cl)cc1F

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.65
THRB P10828 4/20 0.65
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
SMPD1 P17405 4/20 0.50
PLA2G2D Q9UNK4 1/20 0.50
PTPN11 Q06124 1/20 0.50
PLA2G2A P14555 1/20 0.48
S1PR2 O95136 1/20 0.48
S1PR1 P21453 1/20 0.48
S1PR3 Q99500 1/20 0.48
LPAR2 Q9HBW0 1/20 0.48
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428136 1.00 THRA (0.65) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL9626600 1.00 THRA (0.65) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL9626635 1.00 THRA (0.65) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL10527065 1.00 THRA (0.65) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL10359036 0.89 PTPN11 (0.58) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL9440582 0.89 PTPN11 (0.58) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL9650967 0.89 PTPN11 (0.58) THRATHRBALDH1A1HPGDSMPD1
SCHEMBL9440043 0.88 THRA (0.68) THRATHRBALDH1A1HPGDPLA2G2D
SCHEMBL9437150 0.88 THRA (0.68) THRATHRBALDH1A1HPGDPLA2G2D
SCHEMBL9440284 0.88 THRA (0.68) THRATHRBALDH1A1HPGDPLA2G2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993017-B optically active additive, liquid crystal formula and forming method thereof, and liquid crystal display IND TECH RES INST 2015-04-29 CN disclosed
US-8449953-B2 Chiral dopants, liquid crystal matrix and manufacturing method thereof and liquid crystal display INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-05-28 US disclosed
CN-102993017-A Optically active additive, liquid crystal formula and forming method thereof, and liquid crystal display IND TECH RES INST 2013-03-27 CN disclosed
US-20130063693-A1 CHIRAL DOPANTS, LIQUID CRYSTAL MATRIX AND MANUFACTURING METHOD THEREOF AND LIQUID CRYSTAL DISPLAY INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-03-14 US disclosed
EP-0335348-B2 Mesomorphic compound, ferroelectric liquid crystal composition containing same and ferroelectric liquid crystal device CANON KK (JP) 2002-02-27 EP disclosed
EP-0335348-B1 Mesomorphic compound, ferroelectric liquid crystal composition containing same and ferroelectric liquid crystal device CANON KK (JP) 1996-03-20 EP disclosed
EP-0418922-B1 Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same CANON KK (JP) 1995-04-12 EP disclosed
EP-0315193-B1 Optically active compound and chiral liquid crystal composition containing the same NIPPON TELEGRAPH & TELEPHONE (JP) 1994-04-06 EP disclosed
US-5200109-A 4-substituted-3-fluorophenyl-thiadiazole derivatives; high speed responsiveness, heat resistance, displaying CANON KABUSHIKI KAISHA (JP) 1993-04-06 US disclosed
EP-0188222-B1 NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-04-29 EP disclosed
US-5059345-A Spontaneous polarization in wide temperature range and high speed response NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-22 US disclosed
US-5034151-A Laminate with 1,3,4-oxadiazole compoumd as liquid crystal CANON KABUSHIKI KAISHA (JP) 1991-07-23 US disclosed
EP-0418922-A2 Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1991-03-27 EP disclosed
US-4943386-A FERROELECTRIC, GOOD RESPONSE AND MEMORY DAINIPPON INK & CHEMICALS, INC. (JP) 1990-07-24 US disclosed
EP-0335348-A2 Mesomorphic compound, ferroelectric liquid crystal composition containing same and ferroelectric liquid crystal device CANON KABUSHIKI KAISHA (JP) 1989-10-04 EP disclosed
EP-0315193-A2 Optically active compound and chiral liquid crystal composition containing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-05-10 EP disclosed
US-4828754-A TILT-TYPE CHIRAL SMECTIC PHASE DAINIPPON INK & CHEMICALS, INC. (JP) 1989-05-09 US disclosed
EP-0256303-A2 Liquid crystal compounds having fluorine-containing core POLAROID CORPORATION (US) 1988-02-24 EP disclosed
EP-0188222-A2 Novel liquid cristalline compounds having substituents DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130063693-A1 CHIRAL DOPANTS, LIQUID CRYSTAL MATRIX AND MANUFACTURING METHOD THEREOF AND LIQUID CRYSTAL DISPLAY CNPY2, YBX3, CCR3 THRA 2832/4885THRB 2863/4885ALDH1A1 3647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.