Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 19/20 | 1.00 |
| ▸ | SRD5A2 | P31213 | 8/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | THPO | P40225 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523351 | 1.00 | SRD5A1 (1.00) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8377383 | 0.94 | SRD5A1 (0.88) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8072086 | 0.93 | SRD5A1 (0.88) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8072089 | 0.93 | SRD5A1 (0.88) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL7522489 | 0.93 | SRD5A1 (0.86) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8072585 | 0.93 | SRD5A1 (0.86) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL7522482 | 0.93 | SRD5A1 (0.86) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8072591 | 0.93 | SRD5A1 (0.86) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8074422 | 0.92 | SRD5A1 (0.85) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8074418 | 0.92 | SRD5A1 (0.85) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970105-B1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 2002-02-27 | — | — | EP | claimed |
| EP-0902790-B1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN SPA (IT) | 2000-08-16 | — | — | EP | claimed |
| EP-0970105-A1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-12 | — | — | EP | claimed |
| WO-1999035161-A1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 1999-07-15 | — | — | WO | claimed |
| US-20250295634-A1 | USE OF ANTIANDROGENS TO TREAT SEPSIS | RHODE ISLAND HOSPITAL | 2025-09-25 | — | — | US | disclosed |
| EP-0970105-B1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 2002-02-27 | — | — | EP | disclosed |
| US-6284887-B1 | PREPARING 17.BETA.-CARBOXAMIDO-4-AZASTEROIDS STARTING FROM THE CORRESPONDING 17.BETA.-CARBONYLIMIDAZOLE DERIVATIVES. | PHARMACIA & UPJOHN SPA (IT) | 2001-09-04 | — | — | US | disclosed |
| US-6121449-A | Process for preparing carboxamido-4-azasteroids | PHARMACIA & UPJOHN SPA (IT) | 2000-09-19 | — | — | US | disclosed |
| EP-0902790-B1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN SPA (IT) | 2000-08-16 | — | — | EP | disclosed |
| EP-0902790-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997040062-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250295634-A1 | USE OF ANTIANDROGENS TO TREAT SEPSIS | SHBG, AR, HSD17B11 | SRD5A1 12/4885SRD5A2 11/4885LMNA 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.