SCHEMBL7523552

SCHEMBL7523552

CC(=O)Oc1ccc(C#Cc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.61
MAPT P10636 4/20 0.58
FFAR1 O14842 4/20 0.58
GAA P10253 3/20 0.58
ALDH1A1 P00352 1/20 0.58
HSP90AA1 P07900 1/20 0.58
LMNA P02545 2/20 0.53
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MAPK1 P28482 1/20 0.46
APP P05067 1/20 0.46
BACE1 P56817 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8506449 0.93 ELANE (0.54) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL16327448 0.92 LMNA (0.61) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL8582113 0.92 ELANE (0.53) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL20212095 0.89 FFAR1 (0.51) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL19051632 0.87 BACE1 (0.50) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL24554847 0.87 FFAR1 (0.49) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL20212072 0.86 LMNA (0.55) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL20211707 0.85 BACE1 (0.51) ELANEMAPTFFAR1GAAALDH1A1
SCHEMBL10807264 0.85 HSD17B10 (0.71) ELANEMAPTGAAALDH1A1HSP90AA1
SCHEMBL15611000 0.84 CYP3A4 (0.56) ELANEMAPTFFAR1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US claimed
US-9145519-B2 Crosslinkable aromatic polyester TICONA LLC (US) 2015-09-29 US claimed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO claimed
US-20140088247-A1 Crosslinkable Aromatic Polyester TICONA LLC (US) 2014-03-27 US claimed
CN-114644875-A Adhesion promoting photoresist underlayer composition 罗门哈斯电子材料有限责任公司 2022-06-21 CN disclosed
CN-113589646-A Coating composition and method of forming an electronic device 罗门哈斯电子材料有限责任公司 2021-11-02 CN disclosed
US-11001013-B2 Pre-preg and composite products comprising fibers and a liquid crystal thermoset precursor ALLOTROPICA TECHNOLOGIES INC. (US) 2021-05-11 US disclosed
CN-108148180-B Aromatic resin for underlayer 罗门哈斯电子材料有限责任公司 2020-09-11 CN disclosed
CN-111142328-A Aromatic bottom layer 罗门哈斯电子材料有限责任公司 2020-05-12 CN disclosed
EP-3405513-B1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECH INC (US) 2020-03-18 EP disclosed
US-20190039331-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. 2019-02-07 US disclosed
EP-3405513-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR Allotropica Technologies Inc. (US) 2018-11-28 EP disclosed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO disclosed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO disclosed
EP-1260270-A1 Preparation and use of palladium catalysts for cross coupling reactions BAYER AG (DE) 2002-11-27 EP disclosed
US-20020173421-A1 Preparation and use of palladium catalysts for cross-coupling reactions BAYER AKTIENGESELLSCHAFT (DE) 2002-11-21 US disclosed
EP-0889920-B1 POLYPHENYLENE OLIGOMERS AND POLYMERS DOW CHEMICAL CO (US) 2002-02-13 EP disclosed
US-6288188-B1 ACETYLENIC POLYMERS; INTEGRATED CIRCUITS, DIELECTRICS, MICROELECTRONICS THE DOW CHEMICAL COMPANY 2001-09-11 US disclosed
US-5965679-A BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS THE DOW CHEMICAL COMPANY (US) 1999-10-12 US disclosed
EP-0283309-A2 1,2-1,4 Addition reaction sequence leading to diphenylacetylenes McNeilab, Inc. (US) 1988-09-21 EP disclosed