Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731376 | 1.00 | TLR2 (0.60) | TLR2KMT2ATNFMDM4TP53 | |
| SCHEMBL13811918 | 1.00 | TLR2 (0.60) | TLR2KMT2ATNFMDM4TP53 | |
| SCHEMBL3792460 | 0.92 | KMT2A (0.56) | TLR2KMT2ATNF | |
| SCHEMBL3795683 | 0.92 | KMT2A (0.56) | TLR2KMT2ATNF | |
| SCHEMBL3795594 | 0.92 | KMT2A (0.56) | TLR2KMT2ATNF | |
| SCHEMBL3795988 | 0.91 | TLR2 (0.53) | TLR2KMT2ATNF | |
| SCHEMBL753167 | 0.90 | KMT2A (0.54) | TLR2KMT2ATNFCASP3 | |
| SCHEMBL13660232 | 0.90 | KMT2A (0.54) | TLR2KMT2ATNFCASP3 | |
| SCHEMBL31348933 | 0.90 | TLR2 (0.52) | TLR2KMT2A | |
| SCHEMBL31348950 | 0.90 | TLR2 (0.52) | TLR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138140-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2012-03-20 | — | — | US | disclosed |