Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752372 | 1.00 | TLR2 (0.60) | TLR2KMT2ATNFMDM4TP53 | |
| SCHEMBL13811918 | 1.00 | TLR2 (0.60) | TLR2KMT2ATNFMDM4TP53 | |
| SCHEMBL3792460 | 0.92 | KMT2A (0.56) | TLR2KMT2ATNF | |
| SCHEMBL3795683 | 0.92 | KMT2A (0.56) | TLR2KMT2ATNF | |
| SCHEMBL3795594 | 0.92 | KMT2A (0.56) | TLR2KMT2ATNF | |
| SCHEMBL3795988 | 0.91 | TLR2 (0.53) | TLR2KMT2ATNF | |
| SCHEMBL753167 | 0.90 | KMT2A (0.54) | TLR2KMT2ATNFCASP3 | |
| SCHEMBL13660232 | 0.90 | KMT2A (0.54) | TLR2KMT2ATNFCASP3 | |
| SCHEMBL31348933 | 0.90 | TLR2 (0.52) | TLR2KMT2A | |
| SCHEMBL31348950 | 0.90 | TLR2 (0.52) | TLR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580923-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2012-10-18 | — | — | US | disclosed |
| US-8138140-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1696945-B1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | UNIV NORTHWESTERN (US) | 2012-01-18 | — | — | EP | disclosed |
| CN-102225964-A | Self-assembling peptide amphiphiles and related methods for growth factor delivery | UNIV NORTHWESTERN | 2011-10-26 | — | — | CN | disclosed |
| EP-2314305-A2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | Northwestern University (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-7544661-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2009-06-09 | — | — | US | disclosed |
| EP-1696945-A4 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | UNIV NORTHWESTERN (US) | 2007-03-21 | — | — | EP | disclosed |
| CN-1905892-A | Self-assembling peptide amphiphiles and related methods for growth factor delivery | UNIV NORTHWESTERN (US) | 2007-01-31 | — | — | CN | disclosed |
| EP-1696945-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20050209145-A1 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | ENERGY, UNITED STATES DEPARTMENT OF | 2005-09-22 | — | — | US | disclosed |
| WO-2005056039-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | TLR2 1999/4885KMT2A 4467/4885TNF 1188/4885 |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | TLR2 1999/4885KMT2A 4467/4885TNF 1188/4885 |
| US-20050209145-A1 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | HDGF, HDGFL3, IAPP | TLR2 1999/4885KMT2A 4467/4885TNF 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.