Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912827 | 0.85 | SLC1A3 (0.33) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8909706 | 0.79 | SLC1A3 (0.40) | TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7704000 | 0.79 | SLC1A3 (0.40) | TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7704009 | 0.79 | SLC1A3 (0.40) | TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10011315 | 0.74 | TP53 (0.38) | TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10912831 | 0.74 | LMNA (0.30) | — | |
| SCHEMBL10011394 | 0.72 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL1053131 | 0.72 | SLC1A3 (0.31) | TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10011528 | 0.71 | — | — | |
| SCHEMBL10511809 | 0.70 | TP53 (0.35) | TP53SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126225-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED TRIALKYLSILYLOXYMALONIC-ACID DINITRILES | BAYER AG (DE) | 1986-11-26 | — | — | EP | claimed |
| US-4620022-A | REACTING TRIALKYLSILYL CYANIDE WITH ACID HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | claimed |
| EP-0076957-B1 | DIAMIDES OF SUBSTITUTED HYDROXYMALONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-04-09 | — | — | EP | claimed |
| EP-0893436-B1 | Process for producing cyanoformate esters | CREANOVA INC (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-0893436-A1 | Process for producing cyanoformate esters | Creanova Inc. (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5852207-A | Process for producing cyanoformate esters | CREANOVA INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-4698333-A | Use of substituted malonic acid derivatives as agents for combating pests | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| US-4620022-A | REACTING TRIALKYLSILYL CYANIDE WITH ACID HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |
| US-4581375-A | Pesticidal novel substituted hydroxymalonic acid amide-thioamides | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-08 | — | — | US | disclosed |