SCHEMBL7524013

SCHEMBL7524013

N#CCCCc1cccc2c1SCCO2

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 8/20 0.57
MTNR1B P49286 1/20 0.53
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7528370 0.96 MTNR1A (0.58) MTNR1AMTNR1B
SCHEMBL7522473 0.81 MTNR1A (0.64) MTNR1AMTNR1B
SCHEMBL7526198 0.81 MTNR1A (0.61) MTNR1AMTNR1B
SCHEMBL7520556 0.81 MTNR1A (0.61) MTNR1AMTNR1B
SCHEMBL7524064 0.80 MTNR1A (0.62) MTNR1AMTNR1B
SCHEMBL7516525 0.78 MTNR1A (0.49) MTNR1AMTNR1B
SCHEMBL8476411 0.77 MTNR1A (0.73) MTNR1AMTNR1BMEN1KMT2A
SCHEMBL7519080 0.77 MTNR1A (0.53) MTNR1A
SCHEMBL7521018 0.74 MTNR1A (0.56) MTNR1AMTNR1B
SCHEMBL8482684 0.73 MTNR1A (0.65) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP disclosed
US-5919814-A Heterocyclic compounds ADIR ET COMPAGNIE (FR) 1999-07-06 US disclosed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP disclosed