Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527604 | 0.88 | LMNA (0.43) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL7521432 | 0.88 | CYP2C19 (0.48) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL7527382 | 0.87 | CYP2C19 (0.69) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL7524831 | 0.83 | LMNA (0.44) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL7530116 | 0.81 | LMNA (0.48) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL11058204 | 0.81 | LMNA (0.47) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL9737493 | 0.79 | LMNA (0.77) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL9316965 | 0.77 | CYP2C19 (0.72) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL7524812 | 0.77 | CYP2C19 (0.43) | CYP2C19HIF1ALMNA | |
| SCHEMBL7532571 | 0.76 | LMNA (0.48) | CYP2C19HIF1ALMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | claimed |
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |