Urethane

Urethane

SCHEMBL7524401

C=CC=C.CCOC(N)=O.N=C=O.N=C=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.60
ALDH1A1 P00352 4/20 0.36
LMNA P02545 3/20 0.34
HSD17B10 Q99714 2/20 0.34
TSHR P16473 3/20 0.34
GAA P10253 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
CYP2C19 P33261 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL11803069 0.89 ALOX15 (0.75) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL27759655 0.89 ALOX15 (0.75) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL1930430 0.89 ALOX15 (0.75) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL407291 0.89 ALOX15 (0.75) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL370763 0.89
Urethane SCHEMBL23701684 0.89 ALOX15 (0.75) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL11444589 0.89 ALOX15 (0.75) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL2223777 0.89 ALOX15 (0.56) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL27825723 0.89 ALOX15 (0.56) ALOX15ALDH1A1LMNAHSD17B10TSHR
Urethane SCHEMBL10779791 0.87 ALOX15 (0.71) ALOX15ALDH1A1LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609208-B1 PRINTABLE CARPET TILE AND METHOD INTERFACE INC (US) 2002-01-23 EP disclosed
EP-0609208-B1 PRINTABLE CARPET TILE AND METHOD INTERFACE INC (US) 2002-01-23 EP disclosed
EP-0957134-A1 Bitumen composition and method INTERFACE, INC. (US) 1999-11-17 EP disclosed
EP-0609208-A1 PRINTABLE CARPET TILE AND METHOD INTERFACE, INC. (US) 1994-08-10 EP disclosed
EP-0609208-A1 PRINTABLE CARPET TILE AND METHOD INTERFACE, INC. (US) 1994-08-10 EP disclosed
WO-1993008325-A1 PRINTABLE CARPET TILE AND METHOD INTERFACE, INC. (US) 1993-04-29 WO disclosed
WO-1993008325-A1 PRINTABLE CARPET TILE AND METHOD INTERFACE, INC. (US) 1993-04-29 WO disclosed
US-5096764-A Backing of thermosetting hydroxyl terminated polybutadiene diisocyanate urethane polymer HEUGA HOLDING BV (NL) 1992-03-17 US disclosed
US-5096764-A Backing of thermosetting hydroxyl terminated polybutadiene diisocyanate urethane polymer HEUGA HOLDING BV (NL) 1992-03-17 US disclosed