SCHEMBL752441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16908941	0.93	KDM5A (0.40)	BRD4KDM5AKDM4CKDM5BPPARG
	SCHEMBL16908921	0.93	BRD4 (0.39)	BRD4KDM5AKDM4CKDM5BPPARG
	SCHEMBL18531618	0.92	BRD4 (0.39)	BRD4KDM5AKDM4CKDM5BPPARG
	SCHEMBL2489447	0.90	BRD4 (0.37)	BRD4KDM5AKDM4CKDM5BPPARG
	SCHEMBL2490161	0.88	BRD4 (0.43)	BRD4KDM5AKDM4CKDM5BKDM2B
	SCHEMBL18531619	0.86	KDM5A (0.38)	BRD4KDM5AKDM5BPPARGLMNA
	SCHEMBL18531620	0.85	BRD4 (0.38)	BRD4KDM5AKDM4CKDM5BPPARG
	SCHEMBL753782	0.83	KDM5A (0.35)	BRD4KDM5AKDM4CKDM5BKDM2B
	SCHEMBL753747	0.81	KDM5A (0.42)	BRD4KDM5AKDM5BLMNA
	SCHEMBL16921596	0.81	BRD4 (0.43)	BRD4KDM5AKDM4CKDM5BKDM2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.