SCHEMBL2489447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16908941	0.91	KDM5A (0.40)	BRD4KDM5AKDM5BPPARGSMN1; SMN2
	SCHEMBL754597	0.90	BRD4 (0.39)	BRD4LRRK2KDM5AKDM5BMAPT
	SCHEMBL752441	0.90	BRD4 (0.40)	BRD4KDM5AKDM5BPPARGKDM4C
	SCHEMBL16908921	0.89	BRD4 (0.39)	BRD4KDM5AKDM5BPPARGMAOB
	SCHEMBL18531619	0.84	KDM5A (0.38)	BRD4KDM5AKDM5BPPARGSMN1; SMN2
	SCHEMBL18531618	0.83	BRD4 (0.39)	BRD4KDM5AKDM5BPPARGKDM4C
	SCHEMBL18531620	0.82	BRD4 (0.38)	BRD4KDM5AKDM5BPPARGMAOB
	SCHEMBL753747	0.80	KDM5A (0.42)	BRD4KDM5AKDM5BSMN1; SMN2MAPT
	SCHEMBL16921596	0.78	BRD4 (0.43)	BRD4KDM5AKDM5BMAOBKDM4C
	SCHEMBL2490161	0.78	BRD4 (0.43)	BRD4KDM5AKDM5BKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.