Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051994 | 0.87 | KDM1A (0.46) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL17753877 | 0.85 | KDM1A (0.48) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL337877 | 0.83 | OPRD1 (0.48) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL13853714 | 0.83 | OPRD1 (0.51) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL338047 | 0.83 | OPRD1 (0.48) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL6923421 | 0.83 | OPRD1 (0.48) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL1244838 | 0.82 | KDM1A (0.50) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL5654694 | 0.82 | KDM1A (0.50) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL27353398 | 0.82 | KDM1A (0.50) | KDM1AOPRD1FPR3FPR2SMN1; SMN2 | |
| SCHEMBL80021 | 0.82 | PDE8B (0.49) | KDM1AOPRD1SMN1; SMN2PDE8BATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |