SCHEMBL752463

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752207	0.83	EDNRA (0.52)	EDNRAABCG2LMNAMAPT
	SCHEMBL752461	0.82	EDNRA (0.53)	EDNRAMAOBBCHEACHEABCG2
	Hydrochloric Acid SCHEMBL754760	0.82	EDNRA (0.51)	EDNRAABCG2LMNAMAPT
	SCHEMBL1483627	0.82	PPARG (0.67)	EDNRAMAOBBCHEACHEPPARG
	SCHEMBL29502918	0.78	EDNRA (0.56)	EDNRAL3MBTL1
	SCHEMBL18702961	0.78	EDNRA (0.56)	EDNRAL3MBTL1
	SCHEMBL16151329	0.78	PPARG (0.62)	EDNRAMAOBBCHEACHEPPARG
	SCHEMBL752462	0.77	POLB (0.51)	EDNRAMAOBABCG2SRD5A2L3MBTL1
	SCHEMBL2809200	0.77	EDNRA (0.52)	EDNRAMAOBTDP1LMNASRD5A2
	SCHEMBL27651725	0.77	MEN1 (0.60)	EDNRAMAOBBCHEACHEPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.