Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002353 | 0.87 | KDM4E (0.35) | ALDH1A1 | |
| SCHEMBL25492666 | 0.86 | TSHR (0.43) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL7775122 | 0.86 | TSHR (0.43) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL24927982 | 0.86 | TSHR (0.43) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL11150782 | 0.84 | EPHX1 (0.44) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL25100338 | 0.84 | EPHX1 (0.44) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL19006418 | 0.84 | EPHX1 (0.44) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Hydrochloric Acid SCHEMBL22575381 | 0.84 | TSHR (0.42) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL7770644 | 0.84 | EPHX1 (0.44) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL8964539 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187820-A1 | SUBSTITUTED UREAS | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001000602-A1 | SUBSTITUTED UREAS | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |