Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293163 | 0.77 | TDP1 (0.44) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL13310247 | 0.77 | MAPT (0.44) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL14460086 | 0.76 | SIRT2 (0.45) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10756355 | 0.76 | SIRT2 (0.45) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18556340 | 0.72 | MAPT (0.55) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL30602494 | 0.72 | MAPT (0.55) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL27498463 | 0.71 | MAPT (0.38) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL12023611 | 0.70 | SIRT2 (0.81) | MAPTL3MBTL1KDM4EGAASIRT2 | |
| SCHEMBL11320506 | 0.69 | MAPT (0.50) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL13310277 | 0.67 | CA2 (0.55) | MAPTMEN1KMT2ATDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873989-B1 | Process for the preparation of distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2002-03-20 | — | — | EP | claimed |
| US-6031126-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| US-5952524-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | claimed |
| EP-0873989-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | claimed |
| EP-0873988-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | claimed |
| EP-0873989-B1 | Process for the preparation of distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| EP-0849244-B1 | Process for the preparation of distyryl-biphenylic compounds | CIBA SC HOLDING AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-6031126-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| US-5969204-A | Process for the production of distyryl-biphenyl compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5952524-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0873988-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| EP-0873989-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| EP-0849244-A1 | Process for the preparation of distyryl-biphenylic compounds | Ciba SC Holding AG (CH) | 1998-06-24 | — | — | EP | disclosed |