Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL12506211 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TSHRACHETPMTSELL | |
| Hydrochloric Acid SCHEMBL11595023 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TSHRACHETPMTSELL | |
| SCHEMBL341533 | 0.89 | ALDH1A1 (0.67) | ALDH1A1TSHRACHETPMTSELL | |
| SCHEMBL26115 | 0.89 | — | — | |
| SCHEMBL25401798 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTSELL | |
| SCHEMBL23202757 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTSELL | |
| SCHEMBL25403949 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTSELL | |
| SCHEMBL432597 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTSELL | |
| Hydrochloric Acid SCHEMBL2443762 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTSELL | |
| SCHEMBL843588 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTSELL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661591-A | CO (carbon monoxide)2Lewis base monomer for reaction adhesion-promoting type surface polymerization agent and preparation method thereof | 中国石油大学(华东) | 2025-03-21 | — | — | CN | claimed |
| CN-113045597-B | Visible light driven boron-doped thick photochromic material and preparation and application thereof | 湖南大学 | 2022-05-24 | — | — | CN | claimed |
| CN-114249759-A | Bora Z-type acene derivative and preparation method and application thereof | 吉林大学 | 2022-03-29 | — | — | CN | claimed |
| CN-113045597-A | Visible light driven boron-doped thick photochromic material and preparation and application thereof | 湖南大学 | 2021-06-29 | — | — | CN | claimed |
| CN-119661591-A | CO (carbon monoxide)2Lewis base monomer for reaction adhesion-promoting type surface polymerization agent and preparation method thereof | 中国石油大学(华东) | 2025-03-21 | — | — | CN | disclosed |
| CN-119613611-A | Be used for marine CO2CO for controlling thick oil and gas channeling2Chemical reaction adhesion-promoting type surface-accumulating agent, and preparation method and application thereof | 中国石油大学(华东) | 2025-03-14 | — | — | CN | disclosed |
| CN-119219684-A | Polycyclic aromatic compound, polymer compound, material for organic device, organic electroluminescent element, display device, and lighting device | 国立大学法人京都大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-118027085-A | Organic electroluminescent compound and application thereof | 宁波卢米蓝新材料有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112839922-B | Hydrophilic and in particular water-soluble DBOV derivatives | 马克斯·普朗克索赔科学公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117756603-A | Method for preparing cyclohexanol by photocatalysis cyclohexene hydration reaction | 浙江大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116284081-A | Perylene boron-nitrogen doped condensed ring aromatic hydrocarbon, and synthetic method and application thereof | 天津理工大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115960123-A | Boron hetero-molecular carbon compound with near-infrared absorption and preparation method and application thereof | 吉林大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-113045597-B | Visible light driven boron-doped thick photochromic material and preparation and application thereof | 湖南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114249759-A | Bora Z-type acene derivative and preparation method and application thereof | 吉林大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-113045597-A | Visible light driven boron-doped thick photochromic material and preparation and application thereof | 湖南大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-101657219-A | Novel cascade polymer complexes, their preparation method and the pharmaceutical composition that comprises them | BAYER SCHERING PHARMA AG | 2010-02-24 | — | — | CN | disclosed |
| EP-0863882-B1 | AMINO SUBSTITUTED PYRIMIDINES AND TRIAZINES | JANSSEN PHARMACEUTICA NV (BE) | 2002-02-06 | — | — | EP | disclosed |
| US-6288060-B1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS; ANXIOLYTIC, ANTIDEPRESSANT, ANTIINFLAMMATORY AGENTS; EATING DISORDERS | NEUROCRINE BIOSCIENCES, INC. | 2001-09-11 | — | — | US | disclosed |
| EP-0863882-A1 | AMINO SUBSTITUTED PYRIMIDINES AND TRIAZINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997014684-A1 | AMINO SUBSTITUTED PYRIMIDINES AND TRIAZINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-04-24 | — | — | WO | disclosed |