SCHEMBL7525319

SCHEMBL7525319

Cc1cc(NC(=O)Cc2cc(C(=N)N)ccc2O)ccc1C(=O)N1CCCC1C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 4/20 0.42
PRSS1 P07477 2/20 0.42
PLAU P00749 3/20 0.39
HPN P05981 1/20 0.39
DPP4 P27487 2/20 0.38
F2 P00734 5/20 0.38
VNN1 O95497 1/20 0.38
ANO1 Q5XXA6 2/20 0.37
SPHK1 Q9NYA1 4/20 0.37
SPHK2 Q9NRA0 3/20 0.37
PLAT P00750 2/20 0.37
PLG P00747 1/20 0.37
HSD11B1 P28845 1/20 0.36
PREP P48147 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7124790 0.99 F10 (0.41) F10PRSS1PLAUHPNDPP4
SCHEMBL5099780 0.90 F10 (0.42) F10PRSS1PLAUF2PLAT
Hydrochloric Acid SCHEMBL5091399 0.90 F10 (0.42) F10PRSS1PLAUF2PLAT
SCHEMBL2997836 0.85 F10 (0.55) F10PRSS1PLAUF2ANO1
SCHEMBL5094210 0.84 F10 (0.54) F10PRSS1PLAUF2ANO1
Hydrochloric Acid SCHEMBL5089043 0.84 F10 (0.54) F10PRSS1PLAUF2ANO1
Hydrochloric Acid SCHEMBL5099667 0.84 F10 (0.53) F10PRSS1PLAUF2ANO1
Hydrochloric Acid SCHEMBL7116807 0.83 SPHK1 (0.49) F10PRSS1F2VNN1SPHK1
SCHEMBL7123529 0.80 F10 (0.39) F10PRSS1HPNF2ANO1
Hydrochloric Acid SCHEMBL7114852 0.79 F10 (0.39) F10PRSS1HPNF2ANO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity SERPINC1, TFPI, F2 F10 30/4885PRSS1 879/4885PLAU 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.