SCHEMBL752534

SCHEMBL752534

N[C@@H](Cc1ccccc1O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.60
PKM P14618 2/20 0.60
PTGS1 P23219 2/20 0.60
ALPI P09923 1/20 0.60
XIAP P98170 1/20 0.60
HIF1A Q16665 4/20 0.59
KDM4E B2RXH2 4/20 0.59
USP2 O75604 3/20 0.59
MAPT P10636 3/20 0.59
RECQL P46063 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
MEN1 O00255 2/20 0.59
LMNA P02545 2/20 0.59
BLM P54132 2/20 0.59
PMP22 Q01453 2/20 0.59
KMT2A Q03164 2/20 0.59
ALOX15 P16050 2/20 0.59
HSD17B10 Q99714 2/20 0.59
ALDH1A1 P00352 2/20 0.59
RGS12 O14924 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29499536 1.00 SLC7A5 (0.60) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL13537519 1.00 SLC7A5 (0.60) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL1249620 1.00 SLC7A5 (0.60) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL31453811 1.00 SLC7A5 (0.60) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL13537520 1.00 SLC7A5 (0.60) SLC7A5PKMPTGS1ALPIXIAP
Hydrochloric Acid SCHEMBL20492680 0.98 SLC7A5 (0.58) SLC7A5PKMPTGS1ALPIXIAP
Hydrochloric Acid SCHEMBL18341961 0.98 SLC7A5 (0.58) SLC7A5PKMPTGS1ALPIXIAP
Phosphoric Acid SCHEMBL28386744 0.89 SLC7A5 (0.49) SLC7A5PKMPTGS1ALPIXIAP
Phosphoric Acid SCHEMBL28264743 0.89 SLC7A5 (0.49) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL13971424 0.88 SLC7A5 (0.69) SLC7A5PKMPTGS1ALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US claimed
WO-2025032025-A1 STABLE GLASSY MATERIAL BASED ON HISTIDINE, ARGININE AND GLUTAMIC ACID AMINO ACIDS VITROPEP (FR) 2025-02-13 WO claimed
CN-116693771-A Mud-resistant water reducer and preparation method thereof 湖南科之杰新材料有限公司 2023-09-05 CN claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20200146989-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE UNIVERSITY OF COPENHAGEN (DK) 2020-05-14 US claimed
CN-109011701-B Oil-water separation material with pH responsiveness and preparation method and application thereof 华南理工大学 2020-04-28 CN claimed
EP-3559016-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE University of Copenhagen (DK) 2019-10-30 EP claimed
CN-106568870-B A kind of detection method irradiating aquatic products dried product 舟山出入境检验检疫局综合技术服务中心 2019-04-02 CN claimed
CN-109011701-A One kind having pH responsiveness water-oil separating material and the preparation method and application thereof 华南理工大学 2018-12-18 CN claimed
EP-1163262-B1 PHENYLALANINE DERIVATIVES US GOV HEALTH & HUMAN SERV (US) 2011-05-11 EP claimed
EP-1753719-B1 SUBSTITUTED PYRROLIDINE-2-ONES NOVARTIS AG (CH) 2010-03-03 EP claimed
US-20080139456-A1 Macrocyclic Sh2 Domain Binding Inhibitors GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2008-06-12 US claimed
WO-2008067270-A1 MACROCYCLIC GRB2 SH2 DOMAIN-BINDING INHIBITORS GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2008-06-05 WO claimed
US-20070172421-A1 Substituted pyrrolidine-2-ones NOVARTIS AG (CH) 2007-07-26 US claimed
EP-1793843-A1 MACROCYCLIC SH2 DOMAIN BINDING INHIBITORS Government of the United States of America, Represented by the Secretary, Department of Health and Human Services (US) 2007-06-13 EP claimed
WO-2006039527-A1 MACROCYCLIC SH2 DOMAIN BINDING INHIBITORS GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-13 WO claimed
US-6977241-B2 SH2 domain binding inhibitors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2005-12-20 US claimed
US-5767158-A FOR BLEACHING SKIN SHISEIDO CO., LTD. (JP) 1998-06-16 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139456-A1 Macrocyclic Sh2 Domain Binding Inhibitors ACP1, PPM1D, LASP1 SLC7A5 1044/4885PKM 3815/4885PTGS1 4075/4885
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 SLC7A5 843/4885PKM 4113/4885PTGS1 4251/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC SLC7A5 378/4885PKM 3229/4885PTGS1 4428/4885
US-20200146989-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE DNPEP, PEPD, IDUA SLC7A5 436/4885PKM 3274/4885PTGS1 4309/4885
US-20070172421-A1 Substituted pyrrolidine-2-ones PRLHR, EPOR, FLT1 SLC7A5 596/4885PKM 434/4885PTGS1 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.