SCHEMBL752548

SCHEMBL752548

COC(=O)CCCCCCCCCC[Si](C)(Cl)Cl

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
LMNA P02545 3/20 0.48
ALDH1A1 P00352 2/20 0.48
RECQL P46063 1/20 0.44
EPHX2 P34913 4/20 0.41
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
KAT2B Q92831 1/20 0.39
GLA P06280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19770564 1.00 TSHR (0.54) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL19770535 0.88 TSHR (0.54) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL395407 0.88 TSHR (0.54) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL19770574 0.86 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL26602961 0.86 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL755820 0.86 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL9244364 0.86 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL19770561 0.86 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL19770532 0.86 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL10362918 0.83 TSHR (0.58) TSHRLMNAALDH1A1RECQLEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-06-22 US disclosed
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-06-22 US disclosed
US-10692542-B2 Coated slider to inhibit contamination accumulation SEAGATE TECHNOLOGY LLC (US) 2020-06-23 US disclosed
US-20200135240-A1 COATED SLIDER TO INHIBIT CONTAMINATION ACCUMULATION SEAGATE TECHNOLOGY LLC 2020-04-30 US disclosed
US-10522192-B1 Coated slider to inhibit contamination accumulation SEAGATE TECHNOLOGY LLC (US) 2019-12-31 US disclosed
US-9685176-B2 Process to inhibit slider contamination during processing SEAGATE TECHNOLOGY LLC (US) 2017-06-20 US disclosed
US-9613658-B2 Contamination reduction head for media SEAGATE TECHNOLOGY LLC (US) 2017-04-04 US disclosed
US-20170032809-A1 SLIDERS HAVING AT LEAST TWO REGIONS ON THE TRAILING EDGE SURFACE SEAGATE TECHNOLOGY LLC (US) 2017-02-02 US disclosed
US-20160343401-A1 CONTAMINATION REDUCTION HEAD FOR MEDIA SEAGATE TECHNOLOGY LLC 2016-11-24 US disclosed
US-9484062-B1 Media cleaning with self-assembled monolayer material SEAGATE TECHNOLOGY LLC (US) 2016-11-01 US disclosed
US-9153256-B2 Slider with self-assembled monolayer pattern SEAGATE TECHNOLOGY LLC (US) 2015-10-06 US disclosed
US-20150179216-A1 CONTAMINATION REDUCTION HEAD FOR MEDIA SEAGATE TECHNOLOGY LLC 2015-06-25 US disclosed
US-20150103444-A1 SLIDER WITH HIGH AND LOW SURFACE ENERGY COATINGS PROXIMATE TRANSDUCER SEAGATE TECHNOLOGY LLC (US) 2015-04-16 US disclosed
US-20150020379-A1 PROCESS TO INHIBIT SLIDER CONTAMINATION DURING PROCESSING SEAGATE TECHNOLOGY LLC 2015-01-22 US disclosed
US-20140377143-A1 FILTER ELEMENT FOR DISC DRIVE ENCLOSURE SEAGATE TECHNOLOGY LLC 2014-12-25 US disclosed
US-8545932-B2 Metallization of a porous silicon zone by in situ reduction and application to a fuel cell COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-10-01 US disclosed
EP-2319956-B1 Metallizing a zone of porous silicon by in situ reduction and application in a fuel cell COMMISSARIAT ENERGIE ATOMIQUE (FR) 2012-03-21 EP disclosed
EP-2319956-A1 Metallizing a zone of porous silicon by in situ reduction and application in a fuel cell Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2011-05-11 EP disclosed
WO-2011042620-A1 FORMATION OF METAL PARTICLES ON A SOLID OXIDE SUBSTRATE HAVING TWO SEPARATE GRAFTED CHEMICAL FUNCTIONS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-04-14 WO disclosed
US-20110086165-A1 METALLIZATION OF A POROUS SILICON ZONE BY IN SITU REDUCTION AND APPLICATION TO A FUEL CELL COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS CCR4, SALL4, CCR2 TSHR 4142/4885LMNA 3546/4885ALDH1A1 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.