SCHEMBL7525484

SCHEMBL7525484

CNC(=O)C(=NOC)c1ccccc1COc1ccc(C(C)=O)cc1C

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.48
ALDH1A1 P00352 3/20 0.41
RXFP1 Q9HBX9 2/20 0.41
MAOB P27338 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ADRB2 P07550 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9277223 1.00 HIF1A (0.48) HIF1AALDH1A1RXFP1MAOBLMNA
SCHEMBL9079513 0.92 HIF1A (0.48) HIF1AMRGPRX4
SCHEMBL7595205 0.90 HIF1A (0.60) HIF1AALDH1A1RXFP1MAOBLMNA
SCHEMBL9232314 0.89 HIF1A (0.46) HIF1APOLBMRGPRX4
SCHEMBL9232327 0.89 HIF1A (0.46) HIF1APOLBMRGPRX4
SCHEMBL8896734 0.89 HIF1A (0.47) HIF1AMAOBMRGPRX4
SCHEMBL8369903 0.89 HIF1A (0.52) HIF1AMAPTMRGPRX4
SCHEMBL6457931 0.89 HIF1A (0.52) HIF1AMAPTMRGPRX4
SCHEMBL6457937 0.89 HIF1A (0.52) HIF1AMAPTMRGPRX4
SCHEMBL8370194 0.89 HIF1A (0.50) HIF1ALMNAPOLBMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873333-B1 PHENYL BENZYL ETHERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDE AND FUNGICIDE BASF AG (DE) 2002-02-13 EP disclosed
US-6060493-A CONTROL OF INSECTS, ARACHNIDS, NEMATODES AND FUSARIUM AND PIRICULARIA FUNGI; CROP PROTECTION, STORAGE, VETERINARIES BASF AKTIENGESELLSCHAFT (DE) 2000-05-09 US disclosed
EP-0873333-A1 PHENYL BENZYL ETHERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDE AND FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed
WO-1997014693-A1 PHENYL BENZYL ETHERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDE AND FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1997-04-24 WO disclosed
US-5545664-A Substituted phenoxymethylphenyl derivatives, their preparation and their use for controlling pests and fungi BASF AKTIENGESELLSCHAFT (DE) 1996-08-13 US disclosed