Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525419 | 0.84 | TSHR (0.42) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL5015252 | 0.84 | TSHR (0.53) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL6631037 | 0.81 | TSHR (0.50) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL1396448 | 0.81 | TSHR (0.50) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL5357461 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL17915493 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL4797316 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL19837991 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL7991304 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL282682 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | claimed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | claimed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |