Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530991 | 0.87 | ABCB1 (0.48) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL3076619 | 0.84 | ALDH1A1 (0.48) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL3055428 | 0.83 | ABCB1 (0.45) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL5698940 | 0.83 | MEN1 (0.52) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL6745840 | 0.81 | MEN1 (0.48) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL3067988 | 0.80 | KMT2A (0.57) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL3069255 | 0.80 | ALDH1A1 (0.49) | ABCB1MEN1KMT2AATMPKM | |
| SCHEMBL7525000 | 0.80 | KDM4E (0.46) | ABCB1MEN1KMT2ACYP2D6POLB | |
| SCHEMBL3065195 | 0.79 | ABCB1 (0.44) | ABCB1MEN1KMT2AATMCYP2D6 | |
| SCHEMBL7533440 | 0.79 | KDM4E (0.48) | ABCB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832079-B1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2002-03-27 | — | — | EP | disclosed |
| US-6002002-A | Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions | BIOREX RESEARCH & DEVELOPMENT CO. (HU) | 1999-12-14 | — | — | US | disclosed |
| EP-0832079-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000251-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 1997-01-03 | — | — | WO | disclosed |