Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA6 | P23280 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755112 | 0.87 | CA12 (0.61) | CA12CA1CA2CA6CA9 | |
| SCHEMBL9651071 | 0.87 | MEN1 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL14408664 | 0.85 | TSHR (0.51) | CA12CA1CA2CA6CA9 | |
| SCHEMBL487507 | 0.85 | HSP90AA1 (0.62) | CA12CA1CA2CA6CA9 | |
| SCHEMBL4109854 | 0.85 | PKM (0.69) | CA12CA1CA2CA6CA9 | |
| SCHEMBL2581138 | 0.83 | KDM4E (0.57) | CA12CA1CA2CA6CA9 | |
| SCHEMBL8131822 | 0.83 | CA1 (0.57) | CA12CA1CA2CA6CA9 | |
| SCHEMBL27519694 | 0.83 | CA1 (0.57) | CA12CA1CA2CA6CA9 | |
| SCHEMBL10950465 | 0.83 | CA12 (0.61) | CA12CA1CA2CA6CA9 | |
| SCHEMBL14273028 | 0.82 | MEN1 (0.58) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711774-B1 | Crystalline cephem-addition salts and process for their preparation | AVENTIS PHARMA GMBH (DE) | 2002-02-13 | — | — | EP | claimed |
| US-5747484-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | claimed |
| US-4562242-A | Branched polycarbonate from carboxy containing diphenol | GENERAL ELECTRIC COMPANY (US) | 1985-12-31 | — | — | US | claimed |
| US-5747484-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |
| US-4562242-A | Branched polycarbonate from carboxy containing diphenol | GENERAL ELECTRIC COMPANY (US) | 1985-12-31 | — | — | US | disclosed |