Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.78 |
| ▸ | GAA | P10253 | 3/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447101 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL5441255 | 0.88 | KDM4E (0.71) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL5452939 | 0.88 | KDM4E (0.89) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6314617 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6314769 | 0.86 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL5445201 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6315872 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6321034 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL5447095 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL5449135 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187615-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000045800-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-08-10 | — | — | WO | disclosed |
| US-4038031-A | REACTION WITH DIAZONIUM COMPOUND | MILES LABORATORIES, INC. (US) | 1977-07-26 | — | — | US | disclosed |