Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526523 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL7529814 | 0.90 | ADORA3 (0.62) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL7529806 | 0.90 | ADORA3 (0.62) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL7526882 | 0.90 | ADORA3 (0.79) | ADORA3ADORA1ADORA2ANT5E | |
| Gr-190178 SCHEMBL6559907 | 0.87 | ADORA3 (1.00) | ADORA3ADORA1 | |
| Gr-190178 SCHEMBL6559897 | 0.87 | ADORA3 (1.00) | ADORA3ADORA1 | |
| SCHEMBL7531536 | 0.83 | ADORA3 (0.68) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL7531527 | 0.83 | ADORA3 (0.68) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL7527254 | 0.82 | ADORA3 (0.66) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL7527246 | 0.82 | ADORA3 (0.66) | ADORA3ADORA1ADORA2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901499-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-04-10 | — | — | EP | claimed |
| US-5998388-A | N6-PHENYL-SUBSTITUTED | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0901499-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | claimed |
| WO-1997043300-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | claimed |
| EP-0901499-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-04-10 | — | — | EP | disclosed |
| US-5998388-A | N6-PHENYL-SUBSTITUTED | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0901499-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043300-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |