Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.55 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256715 | 0.89 | MEN1 (0.71) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL1208087 | 0.89 | MEN1 (0.71) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL17629809 | 0.89 | MEN1 (0.71) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL94122 | 0.87 | MEN1 (0.61) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL2163305 | 0.87 | MEN1 (0.61) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL94489 | 0.87 | MEN1 (0.61) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Propionyl-Carnitine SCHEMBL2231499 | 0.84 | MEN1 (0.82) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Levocarnitine Propionate SCHEMBL2231502 | 0.84 | MEN1 (0.82) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL1830071 | 0.84 | MEN1 (0.57) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| D-Carnitine SCHEMBL11893828 | 0.83 | SLC22A16 (0.80) | MEN1KMT2ACYP1A2HRH1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020025984-A1 | Granulate with high content of L-carnitine or an alkanoyl L-carnitine, particularly suitable for the production of tablets by direct compression | BIOSINT S.P.A. | 2002-02-28 | — | — | US | disclosed |