SCHEMBL752670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10290773	1.00	NPSR1 (0.41)	NPSR1CA12CA1CA2CA9
	SCHEMBL16921546	0.87	NPSR1 (0.39)	NPSR1KDM4EALDH1A1HPGDMEN1
	SCHEMBL756172	0.82	HTT (0.46)	NPSR1CA12CA1CA2CA9
	SCHEMBL756171	0.82	HTT (0.46)	NPSR1CA12CA1CA2CA9
	SCHEMBL16921568	0.81	NPSR1 (0.43)	NPSR1CA12CA1CA2CA9
	SCHEMBL757223	0.81	NPSR1 (0.43)	NPSR1CA12CA1CA2CA9
	SCHEMBL756483	0.77	P4HTM (0.41)	NPSR1KDM4EALDH1A1HPGDMEN1
	SCHEMBL16921554	0.77	NPSR1 (0.39)	NPSR1CA12CA1CA2CA9
	SCHEMBL13351713	0.77	KLKB1 (0.43)	NPSR1KDM4EALDH1A1HPGDMEN1
	SCHEMBL10290772	0.76	NPSR1 (0.42)	NPSR1KDM4EALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.