SCHEMBL7527115

SCHEMBL7527115

C=CCC(=C)OCCCCO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTT P42858 1/20 0.33
ACHE P22303 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7519201 0.94 GAA (0.33) TSHRALDH1A1CYP3A4HTT
SCHEMBL7524537 0.94 GAA (0.33) TSHRALDH1A1CYP3A4HTT
SCHEMBL7523664 0.84
SCHEMBL11251074 0.81 TSHR (0.46) TSHRALDH1A1CYP3A4
SCHEMBL7525922 0.77 MEN1 (0.46) TSHRALDH1A1HTT
SCHEMBL7521892 0.77 MEN1 (0.46) TSHRALDH1A1HTT
SCHEMBL7526337 0.77 MEN1 (0.46) TSHRALDH1A1HTT
SCHEMBL27677575 0.75 TSHR (0.42) TSHRALDH1A1CYP3A4HTTACHE
SCHEMBL14591356 0.73 TSHR (0.43) TSHRALDH1A1CYP3A4ACHE
SCHEMBL8516769 0.70 HTT (0.50) TSHRALDH1A1CYP3A4HTTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637761-B1 Process for the production of water-absorptive contact lens MENICON CO LTD (JP) 2002-03-13 EP disclosed
EP-0589430-B1 Water-absorptive contact lens MENICON CO LTD (JP) 1999-06-16 EP disclosed
US-5502086-A CROSSLINKED POLYMER OF ACRYLATE AND VINYL ESTER MENICON CO., LTD. (JP) 1996-03-26 US disclosed
US-5426133-A Crosslinked, saponified acrylic copolymers; dimensional and storage stability, heat resistance MENICON CO., LTD. (JP) 1995-06-20 US disclosed
EP-0637761-A1 Water-absorptive contact lens and process for its production Menicon Co., Ltd. (JP) 1995-02-08 EP disclosed
EP-0332179-B1 Highly water-absorptive ocular lens material MENICON CO LTD (JP) 1994-09-14 EP disclosed
EP-0589430-A2 Water-absorptive contact lens Menicon Co., Ltd. (JP) 1994-03-30 EP disclosed
US-4920180-A Hydrophilic polymer MENICON CO., LTD. (JP) 1990-04-24 US disclosed
EP-0332179-A2 Highly water-absorptive ocular lens material Menicon Co., Ltd. (JP) 1989-09-13 EP disclosed