SCHEMBL7527146

SCHEMBL7527146

C#CC(C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.50
CYP2D6 P10635 1/20 0.50
LMNA P02545 3/20 0.48
MAPK1 P28482 2/20 0.48
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
CTSD P07339 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28956796 0.83 EPHX1 (0.44) SRCCYP2D6LMNAMAPK1TDP1
SCHEMBL28126918 0.81 L3MBTL1 (0.61) SRCCYP2D6LMNAMAPK1TDP1
SCHEMBL7773819 0.79 SRC (0.52) SRCCYP2D6LMNAMAPK1TDP1
SCHEMBL28245619 0.79 SRC (0.52) SRCCYP2D6LMNAMAPK1TDP1
SCHEMBL28560576 0.78 KMT2A (0.58) LMNAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL10402900 0.77 SRC (0.50) SRCCYP2D6LMNAMAPK1TDP1
SCHEMBL1019171 0.77 TSHR (0.52) SRCCYP2D6LMNAMAPK1TDP1
SCHEMBL10428043 0.77 SRC (0.50) SRCCYP2D6LMNAMAPK1TDP1
Nitrogen SCHEMBL28486091 0.77 ACP3 (0.44) LMNAMAPK1L3MBTL1PTGS2MAPT
SCHEMBL8512745 0.76 SRC (0.48) SRCCYP2D6LMNAMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805796-B1 CELL ADHESION INHIBITORS BIOGEN INC (US) 2002-12-11 EP claimed
JP-59112963-A None JP disclosed
CN-119872033-A High-air-permeability wear-resistant medical composite fabric and preparation method thereof 苏州冰蓝服饰有限公司 2025-04-25 CN disclosed
CN-119872033-A High-air-permeability wear-resistant medical composite fabric and preparation method thereof 苏州冰蓝服饰有限公司 2025-04-25 CN disclosed
WO-2006130688-A2 COMPOUNDS FOR INHIBITING CATHEPSIN ACTIVITY SCHERING CORPORATION (US) 2006-12-07 WO disclosed
JP-S59112963-A ETHYNYLPHENYLACETIC ACID DERIVATIVE SUBSTITUTED WITH HETEROCYCLIC GROUP MITSUBISHI PETROCHEM CO LTD 1984-06-29 JP disclosed