Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680400 | 0.79 | GAA (0.45) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL680401 | 0.79 | GAA (0.45) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14294534 | 0.78 | NOX1 (0.54) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2561256 | 0.78 | NOX1 (0.54) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2561254 | 0.78 | NOX1 (0.54) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14438098 | 0.74 | MAPT (0.50) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8718594 | 0.74 | MAPT (0.50) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8718598 | 0.74 | MAPT (0.50) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL23384997 | 0.71 | MEN1 (0.45) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2213725 | 0.71 | MAPT (0.47) | MAPTGAAALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109018-C | Systhesis of hydrazone beta-keto ester by reaction with diazo ester | MONSANTO CO (US) | 2003-05-21 | — | — | CN | disclosed |
| EP-0923540-B1 | SYNTHESIS OF A HYDRAZONE BETA-KETO ESTER BY THE REACTION WITH A DIAZO ESTER | MONSANTO TECHNOLOGY LLC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6025492-A | Synthesis of a hydrazone β-keto ester by the reaction with a diazo ester | MONSANTO COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
| CN-1234021-A | Synthesis of a hydrazone beta-ketoester by reaction with a diazo ester | MONSANTO CO (US) | 1999-11-03 | — | — | CN | disclosed |
| EP-0923540-A1 | SYNTHESIS OF A HYDRAZONE BETA-KETO ESTER BY THE REACTION WITH A DIAZO ESTER | MONSANTO COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008807-A1 | SYNTHESIS OF A HYDRAZONE β-KETO ESTER BY THE REACTION WITH A DIAZO ESTER | MONSANTO COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |