Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13036340 | 0.87 | PPARG (0.54) | KDM4EGAAOPRM1OPRK1KMT2A | |
| SCHEMBL2828056 | 0.86 | OPRM1 (0.60) | KDM4EGAAOPRM1OPRK1KMT2A | |
| Potassium Ion SCHEMBL7532631 | 0.84 | KDM4E (0.54) | KDM4EGAAOPRM1OPRK1KMT2A | |
| SCHEMBL7525198 | 0.84 | KDM4E (0.54) | KDM4EGAAOPRM1OPRK1KMT2A | |
| SCHEMBL7528163 | 0.83 | KMT2A (0.68) | KDM4EGAAKMT2ARAB9ANPC1 | |
| SCHEMBL7529775 | 0.82 | P2RY12 (0.64) | KDM4EGAAKMT2ARAB9ANPC1 | |
| SCHEMBL25725737 | 0.82 | PARP1 (0.51) | KDM4EGAAKMT2ARAB9ANPC1 | |
| SCHEMBL30175358 | 0.82 | UBE2T (0.61) | KDM4EOPRM1OPRK1KMT2ARAB9A | |
| SCHEMBL2772947 | 0.82 | UBE2T (0.61) | KDM4EOPRM1OPRK1KMT2ARAB9A | |
| SCHEMBL25725661 | 0.80 | KDM4E (0.50) | KDM4EGAAOPRM1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882716-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6046201-A | Pyridinecarboxamide derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0882716-A1 | PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |