⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769533 | 0.79 | — | — | |
| SCHEMBL144007 | 0.77 | — | — | |
| SCHEMBL9019116 | 0.75 | — | — | |
| SCHEMBL231424 | 0.74 | — | — | |
| SCHEMBL3626234 | 0.72 | — | — | |
| SCHEMBL8208077 | 0.72 | — | — | |
| SCHEMBL2449857 | 0.72 | — | — | |
| SCHEMBL979431 | 0.72 | — | — | |
| SCHEMBL3628842 | 0.72 | — | — | |
| SCHEMBL8212987 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3084 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149360-A1 | BIQUATERNARY AMMONIUM SALT COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF | 西藏海思科制药有限公司 | 2024-07-18 | — | — | WO | claimed |
| WO-2024120442-A1 | PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | WO | claimed |
| CN-118027068-A | Compound containing bridged ring and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| EP-3964514-A1 | GINKGOLIDE B DERIVATIVE AND SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Huiling Jinxin (Shanghai) Pharmaceutical Technology Co., Ltd (CN) | 2022-03-09 | — | — | EP | claimed |
| CN-112321573-A | Substituted pyrimidine compound as phosphatidylinositol 3-kinase delta inhibitor and application thereof | 南京圣和药业股份有限公司 | 2021-02-05 | — | — | CN | claimed |
| WO-2020215895-A1 | GINKGOLIDE B DERIVATIVE AND SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 复旦大学 | 2020-10-29 | — | — | WO | claimed |
| EP-3266774-B1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2019-09-04 | — | — | EP | claimed |
| US-10077258-B2 | Substituted pyrimidine compounds as phosphatidylinositol 3-kinase delta inhibitor and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2018-09-18 | — | — | US | claimed |
| US-20180037576-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| EP-3266774-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2018-01-10 | — | — | EP | claimed |
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | claimed |
| WO-2009005839-A2 | COMPOUNDS AND METHODS OF USE | THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) | 2009-01-08 | — | — | WO | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-12042479-B2 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders | INMED PHARMACEUTICALS INC. | 2024-07-23 | — | — | US | disclosed |
| US-20240240048-A1 | POLYROTAXANE HAVING AMINO GROUP | DENKA COMPANY LIMITED (JP) | 2024-07-18 | — | — | US | disclosed |
| EP-0276552-A1 | 1,4-dihydropyridine derivatives and their production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |