Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 16/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 13/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 13/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063967 | 0.88 | CHRNA7 (0.41) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7524152 | 0.80 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7061059 | 0.80 | CHRNA7 (0.54) | CHRNA7 | |
| SCHEMBL7063353 | 0.77 | CHRNA7 (0.44) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7063539 | 0.75 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7062238 | 0.75 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7063496 | 0.74 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7063436 | 0.74 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7061370 | 0.74 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7061942 | 0.74 | CHRNA7 (0.41) | CHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002017358-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |