Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27449238 | 0.91 | KDM4E (0.51) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL1272702 | 0.85 | HTR5A (0.53) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL643810 | 0.82 | KDM4E (0.54) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL14875890 | 0.81 | KDM4E (0.49) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL1272699 | 0.81 | HTR5A (0.50) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| Hno SCHEMBL28954421 | 0.79 | KDM4E (0.50) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL27501809 | 0.76 | HTR5A (0.44) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL1709266 | 0.75 | KDM4E (0.50) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL3969185 | 0.74 | KDM4E (0.54) | KDM4EMAPTGAAAPOBEC3GTDP1 | |
| SCHEMBL19036261 | 0.72 | HDAC6 (0.50) | KDM4EMAPTTDP1HTR5AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |