SCHEMBL7528216

SCHEMBL7528216

CCCCCCCCOC(=O)CCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.40
CNR2 P34972 3/20 0.37
ALOX5 P09917 1/20 0.35
P2RY10 O00398 3/20 0.34
CNR1 P21554 2/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GPR174 Q9BXC1 1/20 0.32
GPR34 Q9UPC5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9229451 0.90 EPHX2 (0.41) EPHX2CNR2P2RY10CNR1ALDH1A1
SCHEMBL13030430 0.90 EPHX2 (0.41) EPHX2CNR2P2RY10CNR1ALDH1A1
SCHEMBL78014 0.90 EPHX2 (0.41) EPHX2CNR2P2RY10CNR1ALDH1A1
SCHEMBL6863921 0.89 EPHX2 (0.39) EPHX2CNR2P2RY10CNR1ALDH1A1
SCHEMBL6471445 0.88 EPHX2 (0.36) EPHX2CNR2ALOX5P2RY10CNR1
SCHEMBL9870753 0.87 CNR1 (0.40) EPHX2CNR1ALDH1A1KDM4E
SCHEMBL7521604 0.87 KDM4E (0.42) ALDH1A1KDM4EHPGD
SCHEMBL22915501 0.87 EPHX2 (0.38) EPHX2CNR2P2RY10CNR1
SCHEMBL12919745 0.84 EPHX2 (0.41) EPHX2ALOX5P2RY10CNR1ALDH1A1
SCHEMBL23533531 0.84 CNR2 (0.41) EPHX2CNR2ALOX5P2RY10CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6489383-B1 SUCH AS 2-(2-HYDROXY-3-(1,1-DI(4-2-(BROMOETHOXY)PHENYL) ETHYL)-5-TERT-BUTYLPHENYL)-2H-BENZOTRIAZOLE FOR USE AS STOVING LACQUER, FINISHING ENAMEL FOR AUTOMOBILES CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-03 US disclosed
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith WOOD MERVIN G (US) 2002-11-14 US disclosed
US-6392056-B1 FOR THERMOPLASTIC RESINS CIBA SPECIALTY CHEMICAL CORPORATION 2002-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith SUV39H1, SUV39H2, PAH EPHX2 1869/4885CNR2 3089/4885ALOX5 2975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.