SCHEMBL9229451

SCHEMBL9229451

CCCCCCCCCCCCOC(=O)CCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.41
CNR1 P21554 2/20 0.37
GAA P10253 2/20 0.35
KMT2A Q03164 1/20 0.35
CNR2 P34972 3/20 0.35
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
P2RY10 O00398 2/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13030430 1.00 EPHX2 (0.41) EPHX2CNR1GAAKMT2ACNR2
SCHEMBL78014 1.00 EPHX2 (0.41) EPHX2CNR1GAAKMT2ACNR2
SCHEMBL9870753 0.96 CNR1 (0.40) EPHX2CNR1GAAKMT2AALDH1A1
SCHEMBL22915501 0.96 EPHX2 (0.38) EPHX2CNR1CNR2P2RY10
SCHEMBL7525719 0.93 GAA (0.38) EPHX2CNR1GAAKMT2A
SCHEMBL6863921 0.92 EPHX2 (0.39) EPHX2CNR1CNR2ALDH1A1TDP1
SCHEMBL6460885 0.92 ALDH1A1 (0.40) EPHX2CNR1CNR2ALDH1A1TDP1
SCHEMBL19216392 0.91 EPHX2 (0.38) EPHX2CNR1ALDH1A1TDP1L3MBTL1
SCHEMBL9615371 0.91 GAA (0.34) EPHX2CNR1GAAKMT2A
SCHEMBL769282 0.91 EPHX2 (0.32) EPHX2CNR1GAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476882-A Containing 2,2,6,6-tetraalkylpiperidine derivative CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
US-5274016-A Crosslinked polyolefin core and stabilizer of a 2,2,6,6-tetramethylpiperidine derivative having at least one ethylenic double bone CIBA-GEIGY CORPORATION (US) 1993-12-28 US disclosed
EP-0296391-B1 LIGHT-STABILIZED POLYMER MICROPARTICLES CONTAINING EPOXY GROUPS CIBA-GEIGY AG (CH) 1993-07-07 EP disclosed
EP-0226538-B1 LIGHT STABILIZED POLYMER MICROPARTICLES Ciba SC Holding AG (CH) 1991-09-11 EP disclosed
US-5032498-A Soluble stabilizers CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4973702-A AMIDES AND ESTERS, UV STABILIZERS FOR PLASTICS AND PHOTOGRAPHIC MATERIALS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
US-4853471-A 2-(2-Hydroxyphenyl)-benztriazoles, their use as UV-absorbers and their preparation CIBA-GEIGY CORPORATION (US) 1989-08-01 US disclosed
EP-0296391-A2 Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY AG (CH) 1988-12-28 EP disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 EP disclosed