SCHEMBL7528255

SCHEMBL7528255

C=CC(=O)OC(CC)CCCOc1cc(C#N)ccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.46
CYP11B1 P15538 2/20 0.46
CYP11B2 P19099 2/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.43
PPARD Q03181 1/20 0.36
KDM4E B2RXH2 5/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 3/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 2/20 0.34
PTGER1 P34995 1/20 0.34
HRH2 P25021 1/20 0.34
HRH1 P35367 1/20 0.34
PDCD1 Q15116 2/20 0.33
CD274 Q9NZQ7 2/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28601736 0.96 CYP19A1 (0.45) CYP19A1CYP11B1CYP11B2PTGDR2PPARD
SCHEMBL7528252 0.88 PPARD (0.41) PTGDR2PPARDKDM4EPKMKMT2A
SCHEMBL7794901 0.86 CYP19A1 (0.46) CYP19A1CYP11B1CYP11B2PTGDR2PPARD
SCHEMBL28601737 0.85 KMT2A (0.39) PTGDR2PPARDKDM4EPKMKMT2A
SCHEMBL28481945 0.79 CYP19A1 (0.52) CYP19A1CYP11B1CYP11B2PTGDR2PPARD
SCHEMBL2036315 0.78 RXRA (0.46) KDM4EPKMKMT2AGAAALDH1A1
SCHEMBL17162486 0.77 PTPN11 (0.46) KDM4ETHRB
SCHEMBL28368937 0.77 KDM4E (0.38) PTGDR2PPARDKDM4EPKMKMT2A
SCHEMBL8840289 0.76 PTGDR2 (0.43) CYP19A1CYP11B1CYP11B2PTGDR2KMT2A
SCHEMBL1359914 0.76 KMT2A (0.49) KDM4EKMT2AALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713784-B1 Data recording medium FUJI XEROX CO LTD (JP) 2002-04-03 EP disclosed
EP-0669548-B1 Optical element and process for producing the same FUJI XEROX CO LTD (JP) 2001-12-12 EP disclosed
US-5891357-A Optical element and method of manufacturing the same, and macromolecular liquid crystal for an optical element FUJI XEROX CO., LTD. (JP) 1999-04-06 US disclosed
US-5707543-A LIGHT SCATTERING AND RADIATION TRANSPARENT MEDIUM ON SUBSTRATES FOR OPTICAL RECORDING MEDIA USING LIQUID CRYSTALS FUJI XEROX CO., LTD. (JP) 1998-01-13 US disclosed
US-5670083-A CROSSLINKED LIQUID CRYSTAL POLYMER FUJI XEROX CO., LTD. (JP) 1997-09-23 US disclosed
US-5671211-A VISIBLE DATA RECORDING LAYER COMPRISING A LIQUID CRYSTAL POLYMER AND A MAGNETIC RECORDING LAYER; CONTRAST, DURABILITY FUJI XEROX CO., LTD. (JP) 1997-09-23 US disclosed
US-5654046-A Optical element FUJI XEROX CO., LTD. (JP) 1997-08-05 US disclosed
US-5589237-A SUBSTRATE WITH RECORDING LAYER CONTAINING SIDE CHAIN LIQUID CRYSTAL COPOLYMER INCLUDING LIQUID CRYSTAL AND NON-LIQUID CRYSTAL MONOMER UNITS CAPABLE OF HYDROGEN BONDING; REPEATEDLY SWITCHABLE BY ACTION OF HEAT, ELECTRICITY, MAGNETISM FUJI XEROX CO., LTD. (JP) 1996-12-31 US disclosed
EP-0713784-A2 Data recording medium FUJI XEROX CO., LTD. (JP) 1996-05-29 EP disclosed
EP-0669548-A1 Optical element and process for producing the same FUJI XEROX CO., LTD. (JP) 1995-08-30 EP disclosed