Acridine

Acridine

SCHEMBL7528429

O=C(Cl)Cl.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.71
HPGD P15428 4/20 0.71
MAPT P10636 4/20 0.71
GLA P06280 4/20 0.71
ACHE P22303 1/20 0.71
HTR3A P46098 1/20 0.52
IKBKB O14920 1/20 0.50
NQO2 P16083 1/20 0.48
MGAM O43451 2/20 0.47
KDM4E B2RXH2 6/20 0.47
GAA P10253 4/20 0.47
STAT3 P40763 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
RAB9A P51151 4/20 0.45
POLB P06746 2/20 0.45
NPC1 O15118 2/20 0.45
LMNA P02545 1/20 0.45
PTBP1 P26599 1/20 0.45
RCE1 Q9Y256 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL8643076 0.93 ALDH1A1 (0.68) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8079545 0.91 ALDH1A1 (0.65) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL4972293 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL3045498 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1772714 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29352289 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8339 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL11500721 0.84 MAPT (0.68) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL4854060 0.84 ALDH1A1 (0.68) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL17141399 0.82 ALDH1A1 (0.83) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423497-B1 LABELING PREFERENTIAL NUCLEOTIDE SEQUENCES; OBTAIN NUCLEIC ACIDS, INCUBATE IN AMPLIFICATION MIXTURE WITH LABEL AND BINDING AGENT, EXPOSE TO LIGHT, RECOVER PRODUCT APPLIED GENE TECHNOLOGIES, INC. 2002-07-23 US disclosed
EP-1192272-A2 METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION Applied Gene Technologies, Inc. (US) 2002-04-03 EP disclosed
US-6187566-B1 COMPLEXES APPLIED GENE TECHNOLOGIES, INC. 2001-02-13 US disclosed
WO-2000053809-A2 METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION APPLIED GENE TECHNOLOGIES, INC. (US) 2000-09-14 WO disclosed
US-5864044-A Syntheses of trisulfonated phthalocyanines and their derivatatives using boron (111) subphthalocyanines as intermediates UNIVERSITE DE SHERBROOKE (CA) 1999-01-26 US disclosed