Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5437598 | 0.86 | KDM4E (0.51) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL6323440 | 0.84 | KDM4E (0.50) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL5440119 | 0.79 | ALDH1A1 (0.51) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL6323491 | 0.79 | KDM4E (0.64) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL5445042 | 0.77 | KDM4E (0.56) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL5439523 | 0.76 | KDM4E (0.58) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL6315801 | 0.76 | ALDH1A1 (0.51) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL6314743 | 0.75 | KDM4E (0.53) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| Bromide SCHEMBL7529525 | 0.74 | KDM4E (0.53) | KDM4ELMNAHSD17B10CASP1CASP7 | |
| SCHEMBL6322575 | 0.74 | KDM4E (0.49) | KDM4ELMNAHSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187615-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2002-03-20 | — | — | EP | claimed |
| WO-2000045800-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-08-10 | — | — | WO | claimed |
| EP-1187615-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000045800-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-08-10 | — | — | WO | disclosed |