Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 5/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.43 |
| ▸ | TUBB | P07437 | 6/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642697 | 0.79 | CA1 (0.56) | CA1CA2ERN1SRCTLR2 | |
| SCHEMBL609426 | 0.79 | ERN1 (0.49) | ERN1MAOB | |
| SCHEMBL18002071 | 0.78 | ERN1 (0.48) | ERN1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8503115 | 0.78 | CA1 (0.51) | CA1CA2ERN1SRCTLR2 | |
| SCHEMBL7525014 | 0.76 | ERN1 (0.48) | ERN1MAOB | |
| SCHEMBL6764760 | 0.76 | TUBB4A (0.44) | CA1CA2TUBB4ATUBBTUBA3C | |
| SCHEMBL7533951 | 0.76 | ERN1 (0.51) | ERN1TLR2TLR1TLR6 | |
| SCHEMBL5373060 | 0.76 | CA1 (0.53) | CA1CA2ERN1SRCTLR2 | |
| SCHEMBL184461 | 0.75 | CA1 (0.51) | CA1CA2ERN1TUBB4ATUBB | |
| SCHEMBL5737981 | 0.75 | CA1 (0.51) | CA1CA2ERN1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187824-B1 | NOVEL (2-SUBSTITUTED-5 - 3-THIENYL) -BENZYL]- 2- ( 2-ISOPROPOXY-5-FLUORO] -PHENOXY) -ETHYL] -AMINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | PF MEDICAMENT (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-6417222-B1 | DRUGS FOR PSYCHOLOGICAL DISORDERS OR COGNITION ACTIVATORS | PIERRE FABRE MEDICAMENT (FR) | 2002-07-09 | — | — | US | disclosed |
| EP-1187824-A2 | NOVEL (2-SUBSTITUTED-5 - 3-THIENYL) -BENZYL]- 2- ( 2-ISOPROPOXY-5-FLUORO] -PHENOXY) -ETHYL] -AMINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000058282-A2 | NOVEL [(2-SUBSTITUTED-5 -[3-THIENYL) -BENZYL]-[2- ([2-ISOPROPOXY-5-FLUORO] -PHENOXY) -ETHYL] -AMINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2000-10-05 | — | — | WO | disclosed |