Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.66 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.66 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.66 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.65 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.63 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582880 | 1.00 | CHRNB4 (0.66) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6585296 | 1.00 | CHRNB4 (0.66) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6591049 | 0.99 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6594795 | 0.99 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7816212 | 0.92 | CHRNA3 (0.61) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7410204 | 0.92 | CHRNA3 (0.61) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7816957 | 0.91 | CHRNA3 (0.60) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7418741 | 0.91 | CHRNA3 (0.60) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7817031 | 0.87 | CHRNB4 (0.72) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7826052 | 0.87 | CHRNB4 (0.72) | CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | LIN NAN-HORNG (US) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | GAP43, SLC18A2, GABRE | CHRNB4 11/4885CHRNA3 10/4885CHRNA7 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.