Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.63 |
| ▸ | FNTB | P49356 | 18/20 | 0.63 |
| ▸ | PGGT1B | P53609 | 17/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665146 | 0.81 | FNTA (0.73) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7592794 | 0.79 | FNTA (0.67) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7159262 | 0.77 | FNTA (0.67) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7680621 | 0.76 | FNTA (0.62) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7713343 | 0.76 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL7713339 | 0.76 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL7685251 | 0.75 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7589813 | 0.75 | FNTA (0.66) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7683462 | 0.75 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL3499079 | 0.75 | FNTA (0.56) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002542155-A | — | — | 2002-12-10 | — | — | JP | claimed |
| EP-1165013-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | claimed |
| EP-1165013-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| US-6335343-B1 | IMIDAZOL-5-YLALKYLPIPERIZINE DERIVATIVES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-01-01 | — | — | US | claimed |
| WO-2000051547-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | claimed |
| US-6335343-B1 | IMIDAZOL-5-YLALKYLPIPERIZINE DERIVATIVES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-01-01 | — | — | US | disclosed |