SCHEMBL7528809

SCHEMBL7528809

CN(C)CCCCNc1c(CO)c2c(c3ccccc13)OC(c1ccccc1)(c1ccccc1)C=C2

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 2/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
SLC2A1 P11166 1/20 0.39
APOBEC3A P31941 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
ACHE P22303 5/20 0.36
HRH3 Q9Y5N1 2/20 0.36
TOP2A P11388 1/20 0.35
TERT O14746 2/20 0.34
HRH2 P25021 1/20 0.33
HRH1 P35367 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
CACNA2D1 P54289 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8127106 0.84 TOP2A (0.33) RAD52NPC1POLBSLC2A1APOBEC3A
SCHEMBL7534162 0.83 EGFR (0.37) RAD52NPC1POLBSLC2A1APOBEC3A
SCHEMBL7528810 0.81
SCHEMBL5180060 0.73 GCGR (0.32) KMT2A
SCHEMBL8128928 0.72 CACNA1B (0.33) NPC1RAB9AACHEHRH3HRH2
SCHEMBL23800733 0.71
SCHEMBL8127111 0.69
SCHEMBL8137464 0.69 RAD52 (0.36) RAD52NPC1POLBRAB9AKMT2A
SCHEMBL6650937 0.66 GPR84 (0.37) NPC1RAB9AACHEALDH1A1
SCHEMBL9185542 0.66 HSD17B10 (0.33) NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313567-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2025-01-29 EP claimed
US-11945895-B2 Photochromic polydiorganosiloxane vinylic crosslinkers ALCON INC. (CH) 2024-04-02 US claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-11833771-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2023-12-05 US claimed
US-20220339895-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-27 US claimed
US-20220281193-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC. (CH) 2022-09-08 US claimed
US-20210284806-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC. (CH) 2021-09-16 US claimed
EP-1037885-B1 NOVEL WATER SOLUBLE PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL INC (US) 2002-03-27 EP claimed
US-12285922-B2 Method for making photofunctional contact lenses ALCON INC. (CH) 2025-04-29 US disclosed
US-12247169-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2025-03-11 US disclosed
US-20240287379-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2024-08-29 US disclosed
US-11999908-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-06-04 US disclosed
US-11945181-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-04-02 US disclosed
US-11945895-B2 Photochromic polydiorganosiloxane vinylic crosslinkers ALCON INC. (CH) 2024-04-02 US disclosed
US-20220339895-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-27 US disclosed
US-20220281193-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC. (CH) 2022-09-08 US disclosed
US-20220126541-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-04-28 US disclosed
US-20210371731-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2021-12-02 US disclosed
US-20210284806-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC. (CH) 2021-09-16 US disclosed
EP-1037885-B1 NOVEL WATER SOLUBLE PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL INC (US) 2002-03-27 EP disclosed