SCHEMBL7529174

SCHEMBL7529174

CCNc1ccc(NC)c2c1C(=O)c1ccccc1C2=O.O=S(=O)(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
MAPK1 P28482 4/20 0.53
TDP1 Q9NUW8 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
RAB9A P51151 3/20 0.53
EGFR P00533 1/20 0.53
PABPC1 P11940 1/20 0.53
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
POLB P06746 4/20 0.50
USP2 O75604 4/20 0.50
LMNA P02545 3/20 0.50
BLM P54132 2/20 0.50
RECQL P46063 2/20 0.50
GAA P10253 1/20 0.50
THRB P10828 1/20 0.50
CFTR P13569 1/20 0.50
APEX1 P27695 1/20 0.50
KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21300705 0.94 MAPT (0.59) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL8700154 0.94 MAPT (0.55) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL29366166 0.87 MEN1 (0.60) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL78525 0.87 MEN1 (0.60) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL30678386 0.87 MEN1 (0.60) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL7529170 0.84 MEN1 (0.52) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL55230 0.82 MAPT (0.74) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL29419222 0.82 MAPT (0.74) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL29358770 0.82 MAPT (0.74) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1
SCHEMBL14582002 0.81 POLB (0.56) MAPTSMN1; SMN2MAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743994-B1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-04-17 EP disclosed
EP-0743994-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-27 EP disclosed
WO-1995021958-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-08-17 WO disclosed