Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529174 | 0.94 | MAPT (0.53) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL78525 | 0.93 | MEN1 (0.60) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL30678386 | 0.93 | MEN1 (0.60) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL29366166 | 0.93 | MEN1 (0.60) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL8698507 | 0.86 | MEN1 (0.55) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL21300705 | 0.86 | MAPT (0.59) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL12659721 | 0.83 | MAPT (0.52) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL8428746 | 0.83 | MEN1 (0.61) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL9163040 | 0.83 | MEN1 (0.53) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL10613217 | 0.83 | ADORA2A (0.61) | MAPTMEN1KMT2APOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759211-A | COLORING SYNTHETIC TEXTILE OR FIBER BLEND | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |
| US-5759211-A | COLORING SYNTHETIC TEXTILE OR FIBER BLEND | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |
| EP-0743994-A1 | ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021958-A1 | ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-08-17 | — | — | WO | disclosed |