SCHEMBL7529334

SCHEMBL7529334

N#Cc1c(C#N)c([N+](=O)[O-])c([N+](=O)[O-])c2c1-c1ccccc1C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 1/20 0.50
PTPRC P08575 3/20 0.44
S100A4 P26447 3/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 5/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
CASP6 P55212 1/20 0.41
HPGD P15428 1/20 0.40
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
MAPK1 P28482 2/20 0.38
TP53 P04637 1/20 0.38
CYP2D6 P10635 1/20 0.38
STAT6 P42226 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919023 0.80 ALDH1A1 (0.57) ALDH1A1CYP3A4TSHRPTPRCS100A4
SCHEMBL295307 0.74 ALDH1A1 (0.49) ALDH1A1CYP3A4PTPRCS100A4NPC1
Methane SCHEMBL4141657 0.73 ALDH1A1 (0.47) ALDH1A1CYP3A4PTPRCS100A4NPC1
Methane SCHEMBL28696439 0.73 ALDH1A1 (0.47) ALDH1A1CYP3A4PTPRCS100A4NPC1
SCHEMBL28251834 0.72 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRPTPRCS100A4
SCHEMBL29658111 0.72 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRPTPRCS100A4
SCHEMBL11676272 0.71 ALDH1A1 (0.51) ALDH1A1CYP3A4TSHRPTPRCS100A4
SCHEMBL10626632 0.71 MAPT (0.53) ALDH1A1CYP3A4TSHRPTPRCS100A4
SCHEMBL11424411 0.70 ALDH1A1 (0.62) ALDH1A1CYP3A4TSHRPTPRCS100A4
SCHEMBL9344552 0.70 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRPTPRCS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002024837-A1 METHOD FOR DENITROGENATION OF OIL FRACTIONS BY FORMING CHARGE TRANSFER COMPLEXES TOTALFINAELF FRANCE (FR) 2002-03-28 WO claimed
WO-2002024837-A1 METHOD FOR DENITROGENATION OF OIL FRACTIONS BY FORMING CHARGE TRANSFER COMPLEXES TOTALFINAELF FRANCE (FR) 2002-03-28 WO disclosed