SCHEMBL7529478

SCHEMBL7529478

Cc1n[nH]c(C)c1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
CHEK1 O14757 1/20 0.56
AKT2 P31751 1/20 0.56
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HTT P42858 2/20 0.47
APOBEC3G Q9HC16 2/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NOTUM Q6P988 1/20 0.46
ACHE P22303 1/20 0.46
HSD17B10 Q99714 1/20 0.46
XDH P47989 1/20 0.45
SLC11A2 P49281 1/20 0.45
DHODH Q02127 1/20 0.45
AR P10275 1/20 0.45
APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8493201 0.87 TDP1 (0.50) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL22126040 0.84 TDP1 (0.48) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL22126016 0.84 IKBKB (0.59) KDM4EALDH1A1TDP1AKT2MEN1
SCHEMBL16209719 0.82 AKT2 (0.79) KDM4EALDH1A1CHEK1AKT2KMT2A
SCHEMBL2319785 0.81 KDM4E (0.46) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL22125938 0.81 MEN1 (0.46) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL8493831 0.80 MAPT (0.45) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL16225740 0.80 TDP1 (0.58) KDM4EALDH1A1TDP1CHEK1AKT2
SCHEMBL22126023 0.78 AR (0.47) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL21262737 0.76 AKT2 (0.70) ALDH1A1CHEK1AKT2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002006890-A2 METHOD FOR PRODUCING NON-LINEAR OPTICAL ORGANIC CRYSTAL FILM REVEO, INC. (US) 2002-01-24 WO claimed
EP-0418916-B1 Optical wavelength converting method FUJI PHOTO FILM CO LTD (JP) 1995-08-09 EP claimed
WO-2025133234-A1 SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF DRAUPNIR BIO APS (DK) 2025-06-26 WO disclosed
US-20230250079-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-08-10 US disclosed
US-20230250079-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-08-10 US disclosed
US-20230250079-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-08-10 US disclosed
US-20230227435-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-07-20 US disclosed
US-20230227435-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-07-20 US disclosed
CN-116209664-A Small molecule modulators of IL-17 利奥制药有限公司 2023-06-02 CN disclosed
EP-4168114-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO Pharma A/S (DK) 2023-04-26 EP disclosed
US-11377425-B1 Small molecule modulators of IL-17 LEO PHARMA A/S (DK) 2022-07-05 US disclosed
WO-2021255086-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2021-12-23 WO disclosed
WO-2021250194-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2021-12-16 WO disclosed
WO-2021250194-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2021-12-16 WO disclosed
EP-3897623-A1 AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17 Leo Pharma A/S (DK) 2021-10-27 EP disclosed
CN-113164448-A Amino acid anilines as small molecule modulators of IL-17 利奥制药有限公司 2021-07-23 CN disclosed
WO-2020127685-A1 AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2020-06-25 WO disclosed
WO-2002008828-A2 COMPOSITE NONLINEAR OPTICAL FILM, METHOD OF PRODUCING THE SAME AND APPLICATIONS OF THE SAME REVEO, INC. (US) 2002-01-31 WO disclosed
WO-2002006890-A2 METHOD FOR PRODUCING NON-LINEAR OPTICAL ORGANIC CRYSTAL FILM REVEO, INC. (US) 2002-01-24 WO disclosed
US-5345545-A Optical fiber device SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377425-B1 Small molecule modulators of IL-17 IL17A, IL15, IL2 KDM4E 1169/4885ALDH1A1 401/4885TDP1 3918/4885
US-20230250079-A1 SMALL MOLECULE MODULATORS OF IL-17 IL17A, IL2, IL23R KDM4E 1325/4885ALDH1A1 490/4885TDP1 3512/4885
US-20230227435-A1 SMALL MOLECULE MODULATORS OF IL-17 IL17A, IL2, IL23R KDM4E 1394/4885ALDH1A1 448/4885TDP1 3281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.