Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529478 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1TDP1DHODHMEN1 | |
| SCHEMBL22126016 | 0.79 | IKBKB (0.59) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8493201 | 0.72 | TDP1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL22126040 | 0.70 | TDP1 (0.48) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5065616 | 0.68 | MAPT (0.52) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL22125938 | 0.68 | MEN1 (0.46) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3954857 | 0.67 | XDH (0.54) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8493831 | 0.67 | MAPT (0.45) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL4709696 | 0.66 | TYMP (0.53) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20915705 | 0.66 | XDH (0.49) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |